
Scientific Publications
01
Journal of Cell Science
Barata-Antunes C, Talaia G, Broutzakis G, Ribas D, De Beule P, Casal M, Stefan CJ, Diallinas G, Paiva S. Interactions of cytosolic tails in the Jen1 carboxylate transporter are critical for trafficking and transport activity. J Cell Sci. 2022 May 15;135(10):jcs260059. doi: 10.1242/jcs.260059. Epub 2022 May 19. PMID: 35437607.
02
mBio
Alves R, Ghasemi F, Van Genecthen W, Wijnants S, Van Goethem O, Barata-Antunes C, Fernandes V, Ataíde P, Gomes-Goncalves A, Vergauwen R, Ma Q, Duarte R, Soares-Silva I, Casal M, Brown AJP, Van Dijck P, Paiva S. 2025. The ATO gene family governs Candida albicans colonisation in the dysbiotic gastrointestinal tract.
doi: 10.1128/mbio.01644-25.
03
Barata-Antunes C, Warmerdam M, de Hulster E, Ribeiro IP, Cardoso C, Fernandes V, Leite B, Casal M, Hernâni-Gerós, Pronk J, Ariño J, Mans R, Paiva S. 2025. Jen1 transport and endocytosis in yeast reveal pH-responsive strategies to prevent metabolites loss. doi https://www.biorxiv.org/content/10.1101/2024.08.01.606176v2
05
Gomes-Goncalves A, Van Genechten W, Ataíde P, Barata Antunes C, Ghasemi F, Casal M, Teixeira MC, Arino J, Brown AJP, Van Dijck P, Paiva S. 2025. Lactic acid influences iron assimilation by a fungal pathogen via the iron reductive uptake pathway. bioRxiv 2025.05.27.656276. doi:10.1101/2025.05.27.656276
04
Ghasemi F, Barata-Antunes C, Pyrris Y, Ataíde P, Alves J, Fernandes V, Alves R, Gomes-Gonçalves A, Casal M, Genechten W Van, Nysten J, Brown AJP, Van Dijck P, Diallinas G, Pittis AA, Soares-Silva I, Paiva S. 2025. Expansion, functional diversification and gene fusion events in the Ato protein family. doi: https://www.biorxiv.org/content/10.1101/2025.05.26.656167v2
06
Ataíde P, Ghasemi F, César-Silva P, Paiva S, Johansson B. 2025. dnaudit + pydnaweb: A lightweight text-based planning and documentation workflow for genetic cloning with automatic verification. bioRxiv 2025.05.31.657172. doi:10.1101/2025.05.31.657172
Selected Past Publications
01
Barata-Antunes C, Alves R, Talaia G et al. Endocytosis of nutrient transporters in fungi: The ART of connecting signaling and trafficking. Comput Struct Biotechnol J 2021;19:1713–37.
02
PLOS Pathogens
Alves R, Barata-Antunes C, Casal M, Brown AJP, Van Dijck P, Paiva S. Adapting to survive: How Candida overcomes host-imposed constraints during human colonization. PLoS Pathog. 2020 May 21;16(5):e1008478. doi: 10.1371/journal.ppat.1008478. PMID: 32437438; PMCID: PMC7241708.
03
mBio
Alves R, Sousa-Silva M, Vieira D, Soares P, Chebaro Y, Lorenz MC, Casal M, Soares-Silva I, Paiva S. Carboxylic Acid Transporters in Candida Pathogenesis. mBio. 2020 May 12;11(3):e00156-20. doi: 10.1128/mBio.00156-20. PMID: 32398310; PMCID: PMC7218280.
04
npj Biofilms and Microbiomes - Nature
Alves R, Kastora SL, Gomes-Gonçalves A, Azevedo N, Rodrigues CF, Silva S, Demuyser L, Van Dijck P, Casal M, Brown AJP, Henriques M, Paiva S. Transcriptional responses of Candida glabrata biofilm cells to fluconazole are modulated by the carbon source. NPJ Biofilms Microbiomes. 2020 Jan 23;6:4. doi: 10.1038/s41522-020-0114-5. PMID: 31993211; PMCID: PMC6978337.
05
Biofouling
Alves R, Mota S, Silva S, F Rodrigues C, P Brown AJ, Henriques M, Casal M, Paiva S. The carboxylic acid transporters Jen1 and Jen2 affect the architecture and fluconazole susceptibility of Candida albicans biofilm in the presence of lactate. Biofouling. 2017 Nov;33(10):943-954. doi: 10.1080/08927014.2017.1392514. Epub 2017 Nov 2. PMID: 29094611.
06
Mota S, Alves R, Carneiro C, Silva S, Brown AJ, Istel F, Kuchler K, Sampaio P, Casal M, Henriques M, Paiva S. Candida glabrata susceptibility to antifungals and phagocytosis is modulated by acetate. Front Microbiol. 2015 Sep 4;6:919. doi: 10.3389/fmicb.2015.00919.
07
Paiva S, Vieira N, Nondier I et al. Glucose-induced ubiquitylation and endocytosis of the yeast Jen1 transporter: role of lysine 63-linked ubiquitin chains. J Biol Chem 2009;284:19228–36
08
Vieira N, Casal M, Johansson B, MacCallum DM, Brown AJ, Paiva S. Functional specialization and differential regulation of short-chain carboxylic acid transporters in the pathogen Candida albicans. Mol Microbiol. 2010 Mar;75(6):1337-54. doi: 10.1111/j.1365-2958.2009.07003.x.
International Communications
Oral communications:
1. Alves R, Ghasemi F, Van Genechten W, Wijnants S, Van Goethem O, Barata-Antunes C, Fernandes V, Gomes-Gonçalves A, Ataíde P, Vergauwen R, Ma Q, Soares-Silva I, Casal M, Brown A, Van Dijck P and Paiva S. Acetate uptake transporter (AceTr) family members of Candida albicans govern colonization in the dysbiotic gut. 39th Small Meeting on Yeast Transport and Energetics (SMYTE) meeting. 28 August 2024 – 1 September 2024. York, England. Oral communication presented by Sandra Paiva.
2. Ghasemi F, Gomes-Gonçalves A, Fernandes V, Barata-antunes C, Alves R, Soares-Silva I, Casal M, Brown A, Van Genechten W, Van Dijck P and Paiva S. The role of Nutrient Transporters in Candida albicans pathogenesis. IV International Meeting of the Portuguese Society of Genetics. October 20, 2023. Braga, Portugal. Oral communication presented by Faezeh Ghasemi.
3. Barata-Antunes C, de Hulster E, Fernandes V, Cardoso C, Riberio IP, Diallinas G, Casal M, Gerós H, Ariño J, Mans R and Paiva S. Unravelling the molecular mechanisms behind pH-induced downregulation of a lactate nutrient transporter. IV International Meeting of the Portuguese Society of Genetics. October 20, 2023. Braga, Portugal. Oral communication presented by Cláudia Barata-Antunes.
4. Gomes-Gonçalves A, Ghasemi F, Barata-Antunes C, Alves R, Casal M, Brown A, Van Genechten W, Van Dijck P and Paiva S. The role of alternative carbon sources in the expression of ATO transporters in Candida albicans. 38th Small Meeting in Yeast Transport and Energetics (SMYTE23). 13-17 September, 2023. Blankenberge, Belgium. Oral communication presented by Alexandra Gonçalves.
5. Sandra Paiva. Carboxylate transport proteins: regulation and trafficking. 38th Small Meeting in Yeast Transport and Energetics (SMYTE23). 13-17 September, 2023. Blankenberge, Belgium. Oral communication presented by Sandra Paiva.
6. Barata-Antunes C, Talaia G, Broutzakis G, Ribas D, De Beule P, Casal M, J. Stefan C, Mans R, Diallinas G and Paiva S. Regulated endocytosis of monocarboxylate transporters in yeast. EMBO workshop: Membrane transporters as essential elements of cellular function and homeostasis. August 23-27, 2022. Chania, Greece. Oral communication presented by Sandra Paiva.
7. Paiva S. Regulation of a yeast monocarboxylate transporter by metabolic signals. ICY15 (International Congress on Yeasts) meets 30 ICYGMB (International Conference on Yeast Genetics and Molecular Biology). August 23-27, 2021. Vienna, Austria. Oral communication presented by Sandra Paiva.
8. Alves R, Lewin S, Timmermans B, Van Ende M, Brunke S, Casal M, Van Dijck and Paiva S. Acetate Transporters and Channels are an integral part of Candida persistence within the human host ICY15 (International Congress on Yeasts) meets 30 ICYGMB (International Conference on Yeast Genetics and Molecular Biology). August 23-27, 2021. Vienna, Austria. Oral communication presented by Rosana Alves.
Poster communications:
9. Gomes-Gonçalves A, Van Genechten W, Ataíde P, Barata-Antunes C, Ghasemi F, Casal M, Teixeira M C, Ariño J, Brown A, Van Dijck P and Paiva S. Iron homeostasis in Candida albicans is modulated by the presence of lactate. 31th Annual BSM Symposium – amAIzing Microbiology: demystifying AI for all microbiologists, February 21, 2025. Brussels, Belgium. Poster communication.
10. Barata-Antunes C, de Hulster E, Talaia G, Broutzakis G, Casal M, J. Stefan C, Diallinas G, Ariño J, Mans R and Paiva S. Endocytic degradation of carboxylate transporters upon metabolic and stress signals. EMBO Workshop Proteostasis: From translation to degradation. 17-21 November 2023. Ericeira, Portugal. Poster communication.
11. Ghasemi F, Gomes-Gonçalves A, Fernandes V, Barata-Antunes C, Alves R, Alves J, Soares-Silva I, Casal M, Brown AJP, Van Genechten W, Van Dijck P and Paiva S. The role of Nutrient Transporters in Candida albicans pathogenesis. IV International Meeting of the Portuguese Society of Genetics (IMPSG), 19-20 October 2023. Braga, Portugal. Poster communication.
12. Barata-Antunes C, de Hulster E, Fernandes V, Cardoso C, Riberio IP, Diallinas G, Casal M, Gerós H, Ariño J, Mans R and Paiva S. Unravelling the molecular mechanisms behind pH-induced downregulation of a lactate nutrient transporter. IV International Meeting of the Portuguese Society of Genetics. October 19-20, 2023. Braga, Portugal. Poster communication.
13. Alves R, Barata-Antunes C, Ghasemi F, Fernandes V, Gonçalves A, Casal M, Brown AJP, Van Dijck P and Paiva S. ATO transporters as essential elements of cellular function and homeostasis in Candida albicans pathogenesis. 10th Congress of European Microbiologists FEMS 2023. July 9-13, 2023. Hamburg, Germany. Poster communication.
14. Alves R, Fernandes V, Ghasemi F, Gonçalves A, Barata-Antunes C, Casal M, Soares-Silva I, Van Dijck P, Brown AJP, Paiva S. Exploring the role of nutrient transporters in Candida pathogenesis. EMBO workshop: Membrane transporters as essential elements of cellular function and homeostasis. August 23-27, 2022. Chania, Greece. Poster communication.
15. Barata-Antunes C, Talaia G, Broutzakis G, Ribas D, De Beule P, Casal M, Stefan CJ,Mans R, Diallinas G and Paiva S. Metabolic induced degradation of yeast plasma membrane carboxylate transporters. EMBO workshop: Membrane transporters as essential elements of cellular function and homeostasis. August 23-27, 2022. Chania, Greece. Poster communication.
15. Barata-Antunes C, de Hulster E, Fernandes V, Cardoso C, Casal M, Gerós H, Mans R and Paiva S. Jen1 transporter endocytosis under alkali stress. The Biochemistry Global Summit, 25th IUBMB Congress, 46th FEBS Congress, 15th PABMB Congress July 9-14, 2022. Lisbon, Portugal. Poster communication.
16. Barata-Antunes C, Talaia G, Broutzakis G, Ribas D, De Beule P, Casal M, Stefan CJ, Mans R, Diallinas G, and Paiva S. Endocytic downregulation of carboxylate transporters in eukaryotic cells. The Lysosomes and Endocytosis Gordon Research Conference. June 19-24, 2022. Andover, United States. Poster communication.
National Communications
Oral communications:
1. Ghasemi F, Barata-Antunes C, Alves J, Ataíde P, Fernandes V, Casal M, Van Genechten W, Nysten J, Van Dijck P, Soares-Silva I and Paiva S. Prediction and characterization of C. albicans Ato proteins’ specificities and structural features. II CBMA Open Day & III PhD|BIO Symposium. February 5, 2025. Braga, Portugal. Oral communication.
2. Ataíde P, Ghasemi F, Barata-Antunes C, Gomes-Gonçalves A, Alves R, Casal M, Brown A, Van Genechten W, Nysten J, Van Dijck P and Paiva S. Characterizing Ato2 proteins: Expression profiles and Subcellular Dynamics in Candida albicans. XXII Jornadas de Biologia de Leveduras Professor Nicolau van Uden. September 20-21, 2024. Curia, Anadia, Portugal. Oral communication.
3. Ghasemi F, Alves R, Barata-Antunes C, Ataíde P, Alves J, Soares-Silva I, Gomes-Gonçalves A, Fernandes V, Casal M, Brown AJP, Van Genechten W, Nysten J, Van Dijck P, Paiva S. Unveiling the Crucial Role of Nutrient Transporters in Candida albicans Pathogenesis. XXII Jornadas de Biologia de Leveduras Professor Nicolau van Uden. September 20-21, 2024. Curia, Anadia, Portugal. Oral communication.
4. Conceição-Leite B, Barata-Antunes C, Wedlich-Söldner R, Schuberth C and Paiva S. Uncovering the Plasma membrane compartmentalization and dynamics of carboxylate transporter proteins in yeast. XXII Jornadas de Biologia de Leveduras, Professor Nicolau van Uden. September 20-21 2024. Curia, Anadia, Portugal. Oral communication.
5. Barata-Antunes C, de Hulster E, Cardoso C, Ribeiro IP, Conceição Leite B, Diallinas G, Casal M, Gerós H, Ariño J, Mans R and Paiva S. pH-dependent downregulation of a yeast nutrient transporter: mechanisms and metabolic implications. XXII Jornadas de Biologia de Leveduras Professor Nicolau van Uden, September 20-21, 2024. Curia, Anadia, Portugal. Oral communication.
6. Ataíde P, Abreu I, Ghasemi F, Barata-Antunes C, Paiva S and Johansson B. Plugging the holes: an intuitive software tool for reproducibility in Molecular Biology. XIII Edition of the Bioinformatics Open Days. March 14-16, 2024. Braga, Portugal. Oral communication.
Poster communications:
7. Ataíde P, Ghasemi F, Barata-Antunes C, Gomes-Gonçalves A, Alves R, Casal M, Brown A, Van Genechten W, Nysten J, Van Dijck P and Paiva S. Fungi and Nutrition: Exploring Ato6 subcellular dynamics in Candida albicans. II CBMA Open Day & III PhD|BIO Symposium. February 5, 2025; Braga, Portugal. Poster communication.
8. Ghasemi F, Barata-Antunes C, Ataíde P, Alves J, Soares-Silva I, Alves R, Gomes-Gonçalves A, Fernandes V, Casal M, Brown AJP, Van Genechten W, Nysten J, Van Dijck P and Paiva S. Differential affinity and expression patterns among Candida albicans Ato family members. I CBMA Open Day & II PhD|Bio Symposium. 2 February 2024. Braga, Portugal. Poster communication.
9. Gomes-Gonçalves A, Van Genechten W, Barata-Antunes C, Ghasemi F, Alves R, Casal M, Ariño J, Brown A, Van Dijck P, and Paiva S. Transcriptional response of Candida albicans cells to the presence of lactic acid and environmental pH. I CBMA Open Day & II PhD|Bio Symposium. 02 February 2024. Braga, Portugal. Poster communication.
10. Ataíde P, Ghasemi F, Barata-Antunes C, Gomes-Gonçalves A, Alves R, Casal M, Brown A, Van Genechten W, Nysten J, Van Dijck P and Paiva S. Fungi and Nutrition: Expression and Subcellular Localization Patterns of Ato2 Transport Protein of Candida albicans. UMinho Research & Innovation Open Days. January 30-31, 2024. Braga, Portugal. Poster communication.
11. Ghasemi F, Barata-Antunes C, Ataíde P, Alves J, Soares-Silva I, Alves R, Gomes-Gonçalves A, Fernandes V, Casal M, Brown AJP, Van Genechten W, Nysten J, Van Dijck P and Paiva S. Candida albicans Acetate transporter orthologues (ATOs): docking and expression studies. UMinho Research & Innovation Open Days. 30-31 January 2024. Braga, Portugal. Poster communication.
12. Barata-Antunes C, de Hulster E, Cardoso C, Conceição Leite B , Fernandes V , Ribeiro IP, Diallinas G, Casal M, Gerós H, Ariño J, Mans R and Paiva S. Decoding alkali stress responses in fungi. UMinho Research & Innovation Open Days, January 30-31, 2024. Braga, Portugal. Poster communication.
13. Gomes-Gonçalves A, Van Genechten W, Barata-Antunes C, Ghasemi F, Alves R, Casal M, Ariño J, Brown A, Van Dijck P, and Paiva S. Transcriptomic analysis of C. albicans cells in distinct metabolic conditions. UMinho Research & Innovation Open Days, January 30-31. Braga, Portugal. Poster communication.
14. Gomes-Gonçalves A, Ghasemi F, Barata-Antunes F, Fernandes V, Alves R, Casal M, Van Genechten W, Van Dijck P, and Paiva S. Metabolic Induced Pathogenesis in Candida albicans: the role of ATO transporters and carboxylic acids. I Symposium PhDBio, February 8, 2023. Braga, Portugal. Poster communication.
Grants & Awards

International Mobilities









